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KMID : 0390220000110020237
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Journal of Clinical Otolaryngology, Head and Neck Surgery
2000 Volume.11 No. 2 p.237 ~ p.240
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Laryngo-Pharyngeal Reflux Events in Patients with Vocal Cord Nodules
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장일환/Il Whan Jang
김찬우/김동영/황수훈/구지영/Chan Woo Kim/Dong Young Kim/Soo Hoon Hwang/Ji Young Ku
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Abstract
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Background and Objectives : Laryngo-pharyngeal reflux(LPR) is believed to be an important etiologic factor
in the development of many inflammatory and neoplastic disorders of the upper aerodigestive tract. But there
have not been well-documented that vocal cord nodules are related with reflux. The purpose of this study is to
determine the relationship between vocal cord nodules and LPR as causative factor. Materials and Method :
Prospectively, Fifteen patients with vocal cord nodules and ten healthy volunteers were studied. Prior to therapy
including larynegal microsurgery, each group underwent espohageal manometry and ambulatory 24hour
double probe pH monitoring. Pharyngeal acid reflux event was deemed acceptable if a decrease in pH below 4
was recorded in all two esophageal and pharyngeal probe. Total reflux socre, percent acid exposure time and
average acid clearance time were measured and compared between two groups. Results : Eleven of the 15
patients(73.3%) had the reflux in pharyngeal probe. Three of the 10 controls(30%) had the reflux. Total feflux
score and percent acid exposure time were significantly higher in patients than in control group but average acid
clearance time was not significantly different between two groups. Conclusion : Prevalence of pharyngeal acid
reflux events is significantly higher in patients with vocal nodules. LPR may be a risk factor for the
development of vocal cord nodules.
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KEYWORD
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